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Mammary Ductoscopy and Intraductal Biopsy for Women at High Risk for Developing Breast Cancer, for Women Presenting with Spontaneous Nipple Discharge, and for Women Diagnosed with Breast Cancer Undergoing Surgery to the Contralateral Breast

Time frame of study:		Ongoing
Location of Study:		Beth Israel Medical Center
Contact:		Continuum Cancer Center Research Program (212) 844-6286

Summary:
Most breast cancers originate in the milk ducts of the breast. They usually grow slowly over ten to fifteen years and remain undetected because the cancer is too small to be found on breast examinations or mammograms. Using a very small endoscope to look within the milk duct may allow detection of these very early cancers. The purpose of this study is to determine the ability of ductoscopy and intraductal biopsy (taking a small sample of tissue from within the duct) to identify abnormal findings or invasive breast cancers that would not have been identified during a routine mammogram.

Eligibility:
This study is open to women who are at high risk for developing breast cancer (including women diagnosed with breast cancer who are undergoing surgery to the undiagnosed breast), and women who have spontaneous nipple discharge. Please call for more information.

Benefits and/or Compensation:
There is no monetary compensation for this study. The information gathered from this study may be beneficial to future patients, and women who participate may gain new information about their breast health.